BDBM81619 2,6,9-Trisubstitute purine, 4

SMILES OCCNc1nc(Nc2ccccc2)c2ncn(CCc3cccc(O)c3)c2n1

InChI Key InChIKey=KGEHYMSXWBXBMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81619   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM81619(2,6,9-Trisubstitute purine, 4)
Affinity DataIC50:  26nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed